Film-Forming Chitosan/Poly (vinyl alcohol)–Poly (hexamethylene biguanide) Antiseptic Spray for Wound Cleansing: A Sustainable Healthcare Approach Aligned with Sustainable Development Goals (SDGs) Completed with Bibliometric Analysis
Keywords:
Antibacterial, Anti-biofilm, Antiseptic spray, Chitosan, PHMB, Wound cleansingAbstract
Proper wound cleansing is a fundamental step in preventing
infection and supporting effective wound management. This
study aimed to develop and evaluate a film-forming antiseptic
spray composed of chitosan, polyvinyl alcohol, and
polyhexamethylene biguanide for wound cleansing
applications. The formulation was prepared using a solutionbased approach and characterized in terms of morphology,
chemical interactions, sprayability, film formation stability,
antibacterial, and antibiofilm performance. The developed
spray demonstrated uniform application, stable film formation,
and effective incorporation of the antimicrobial agent.
Biological evaluations confirmed enhanced antibacterial and
antibiofilm activity because of synergistic interactions between
the biopolymer matrix and the cationic antiseptic component.
This study was further supported by bibliometric evidence
indicating a growing global research focus on wound care
materials and film-forming antiseptic sprays, emphasizing their
relevance to sustainable healthcare innovation. The findings
contribute to the advancement of sustainable wound care
technologies and align with the Sustainable Development
Goals, particularly the goal of promoting good health and wellbeing
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